Hydrogen Peroxide‐Inducible PROTACs for Targeted Protein Degradation in Cancer Cells

Proteolysis‐targeting chimeras (PROTACs) provide a powerful technique to degrade targeted proteins utilizing the cellular ubiquitin‐proteasome system. The major concern is the host toxicity resulting from their poor selectivity. Inducible PROTACs responding to exogenous stimulus, such as light, impr...

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Veröffentlicht in:Chembiochem : a European journal of chemical biology 2023-09, Vol.24 (17), p.e202300422-n/a
Hauptverfasser: Yu, Dehao, Fan, Heli, Zhou, Zhili, Zhang, Ying, Sun, Jing, Wang, Luo, Jia, Yuanyuan, Tian, Junyu, Campbell, Anahit, Mi, Wenyi, Sun, Huabing
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Sprache:eng
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