On the Selectivity in the Synthesis of 3‑Fluoropiperidines Using BF3‑Activated Hypervalent Iodine Reagents
Fluorinated piperidines find wide applications, most notably in the development of novel therapies and agrochemicals. Cyclization of alkenyl N-tosylamides promoted by BF3-activated aryliodine(III) carboxylates is an attractive strategy to construct 3-fluoropiperidines, but it suffers from selectivi...
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Veröffentlicht in: | Journal of organic chemistry 2023-08, Vol.88 (15), p.10946-10959 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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