On the Selectivity in the Synthesis of 3‑Fluoropiperidines Using BF3‑Activated Hypervalent Iodine Reagents

Fluorinated piperidines find wide applications, most notably in the development of novel therapies and agrochemicals. Cyclization of alkenyl N-tosylamides promoted by BF3-activated aryliodine­(III) carboxylates is an attractive strategy to construct 3-fluoropiperidines, but it suffers from selectivi...

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Veröffentlicht in:Journal of organic chemistry 2023-08, Vol.88 (15), p.10946-10959
Hauptverfasser: Pavlović, Radoslav Z., Kop, Tatjana J., Nešić, Marko, Stepanović, Olivera, Wang, Xiuze, Todorović, Nina, Rodić, Marko V., Šmit, Biljana M.
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Sprache:eng
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