Pancreatitis, panniculitis and polyarthritis syndrome: A case report

BACKGROUNDPancreatitis, panniculitis, and polyarthritis (PPP) syndrome is a rare form of pancreatic disease. It is characterized by bullous erythematous skin lesions and arthritis, and both are triggered by pancreatic malfunction. Few cases have been described in the literature thus far. Due to the...

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Veröffentlicht in:World journal of clinical cases 2023, Vol.11 (18), p.4412-4418
Hauptverfasser: Pichler, Hannes, Stumpner, Thomas, Schiller, Dietmar, Bischofreiter, Martin, Ortmaier, Reinhold
Format: Report
Sprache:eng
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Zusammenfassung:BACKGROUNDPancreatitis, panniculitis, and polyarthritis (PPP) syndrome is a rare form of pancreatic disease. It is characterized by bullous erythematous skin lesions and arthritis, and both are triggered by pancreatic malfunction. Few cases have been described in the literature thus far. Due to the inconsistency in its clinical presentation, its diagnosis can be a challenge. Early therapy initiation is essential to reduce mortality; however, there is currently no gold standard for treatment. CASE SUMMARYA 66-year-old polymorbid male patient presented with several superficial abscesses on both lower legs and painful swelling in the knee. Treatment for septic arthritis and septic skin infection over several weeks failed. His general condition deteriorated gradually and worsened with sudden onset of abdominal pain. A diagnosis of necrotizing pancreatitis was made. He subsequently underwent a laparotomy and drainage of the pancreas. Eventually, our patient improved, and his abdominal complaints, knee pain, and dermal lesions resolved. CONCLUSIONPPP syndrome is rare and easily misdiagnosed, as abdominal symptoms may be delayed or absent. Clinicians should consider PPP syndrome if they encounter refractory panniculitis in combination with joint infection.
ISSN:2307-8960
2307-8960
DOI:10.12998/wjcc.v11.i18.4412