The Aqueous Lyophilisate of Alchemilla Kiwuensis Engl. (Rosaceae) Displays Antiepileptogenic and Antiepileptic Effects on PTZ-induced Kindling in rats: Evidence of Modulation of Glutamatergic and GABAergic Pathways Coupled to Antioxidant Properties

Alchemilla kiwuensis Engl. (Rosaceae) (A. kiwuensis) is an herbaceous plant traditionally used by Cameroonians to treat epilepsy and other central nervous system disorders. The present study evaluated the antiepileptogenic and antiepileptic effects of A. kiwuensis (40 mg/kg, 80 mg/kg) following Pent...

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Veröffentlicht in:	Neurochemical research 2023-10, Vol.48 (10), p.3228-3248
Hauptverfasser:	Foutsop, Aurelien Fossueh, Ateufack, Gilbert, Adassi, Blesdel Maxwell, Yassi, Francis Bray, Kom, Tatiana Diebo, Noungoua, Chretien Mbeugangkeng, Petsou, Adolph, Ngoupaye, Gwladys Temkou
Format:	Artikel
Sprache:	eng
Schlagworte:	Alchemilla Animal models Animals Antioxidants Biochemical analysis Biochemistry Biomedical and Life Sciences Biomedicine Catalase Cell Biology Central nervous system Chronic toxicity Convulsions & seizures Epilepsy Glutamatergic transmission Glutamic acid transporter Glutathione Hippocampus IL-1β Inflammation Interleukin 1 Kindling Latency Malondialdehyde Modulation Neurochemistry Neurology Neuromodulation Neurosciences Neurotransmission Original Paper Oxidative stress Pentylenetetrazole Repetition Rosaceae Seizures Toxicity Transaminase Transaminases γ-Aminobutyric acid
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