Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39

Mpox is a zoonotic disease caused by the mpox virus (MPXV), which has gained attention due to its rapid and widespread transmission, with reports from more than 100 countries. The virus belongs to the Orthopoxvirus genus, which also includes variola virus and vaccinia virus. In poxviruses, the RNA c...

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Veröffentlicht in:	Antiviral research 2023-08, Vol.216, p.105663-105663, Article 105663
Hauptverfasser:	Skvara, Petr, Chalupska, Dominika, Klima, Martin, Kozic, Jan, Silhan, Jan, Boura, Evzen
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Humans Methylation Methyltransferases - chemistry Mpox (monkeypox) RNA Caps - metabolism Viral Proteins - genetics
Online-Zugang:	Volltext
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