Diagnostic trajectories of mental disorders in children and adolescents: a cohort study
Mental disorders in children and adolescents may follow different trajectories, such as remission, change of diagnosis, or addition of two or more comorbid diagnoses, showing a heterotypic pattern. This study aims to describe the main diagnostic trajectories across a broad range of mental disorder d...
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| Veröffentlicht in: | European child & adolescent psychiatry 2024-05, Vol.33 (5), p.1481-1494 |
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| creator | Girela-Serrano, Braulio Miguélez-Fernández, Carolina Abascal-Peiró, Sofía Peñuelas-Calvo, Inmaculada Jiménez-Muñoz, Laura Moreno, Manon Delgado-Gómez, David Bello, Hugo J. Nicholls, Dasha Baca-García, Enrique Carballo, Juan José Porras-Segovia, Alejandro |
| description | Mental disorders in children and adolescents may follow different trajectories, such as remission, change of diagnosis, or addition of two or more comorbid diagnoses, showing a heterotypic pattern. This study aims to describe the main diagnostic trajectories across a broad range of mental disorder diagnostic categories, from childhood to adolescence and from adolescence to young adulthood in a clinical population. A prospective study was conducted among a clinical sample of children and adolescents who were aged 3–17 years at the face-to-face baseline interview. Electronic health records of these participants were reviewed 10 years later. The diagnostic stability over time was examined using the kappa coefficient, and factors associated with stability were explored using simple logistic regression. The study included a sample of 691 participants. The kappa coefficient for diagnostic stability across all diagnoses was 0.574 for the transition from childhood to adulthood, 0.614 from childhood to adolescence, and 0.733 from adolescence to adulthood. Neurodevelopmental diagnoses had the highest stability. Factors associated with higher diagnostic stability included family history of mental disorders, receiving psychopharmacological treatment, and symptom severity at baseline. We found a variable diagnostic stability across different diagnoses and age categories. The different life transitions represent complex periods that should not be overlooked from a clinical standpoint. An appropriate transition from child and adolescent mental health services to adult mental health services may have a positive impact on children and adolescents with mental disorders. |
| doi_str_mv | 10.1007/s00787-023-02254-0 |
| format | Article |
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This study aims to describe the main diagnostic trajectories across a broad range of mental disorder diagnostic categories, from childhood to adolescence and from adolescence to young adulthood in a clinical population. A prospective study was conducted among a clinical sample of children and adolescents who were aged 3–17 years at the face-to-face baseline interview. Electronic health records of these participants were reviewed 10 years later. The diagnostic stability over time was examined using the kappa coefficient, and factors associated with stability were explored using simple logistic regression. The study included a sample of 691 participants. The kappa coefficient for diagnostic stability across all diagnoses was 0.574 for the transition from childhood to adulthood, 0.614 from childhood to adolescence, and 0.733 from adolescence to adulthood. Neurodevelopmental diagnoses had the highest stability. Factors associated with higher diagnostic stability included family history of mental disorders, receiving psychopharmacological treatment, and symptom severity at baseline. We found a variable diagnostic stability across different diagnoses and age categories. The different life transitions represent complex periods that should not be overlooked from a clinical standpoint. An appropriate transition from child and adolescent mental health services to adult mental health services may have a positive impact on children and adolescents with mental disorders.</description><identifier>ISSN: 1018-8827</identifier><identifier>EISSN: 1435-165X</identifier><identifier>DOI: 10.1007/s00787-023-02254-0</identifier><identifier>PMID: 37422547</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adolescent ; Adolescents ; Age differences ; Child ; Child & adolescent mental health ; Child and Adolescent Psychiatry ; Child development ; Child, Preschool ; Childhood ; Children ; Classification ; Cohort analysis ; Cohort Studies ; Comorbidity ; Computerized medical records ; Electronic medical records ; Female ; Health records ; Health services ; Humans ; Kappa coefficient ; Life course ; Life transitions ; Male ; Medical diagnosis ; Medical records ; Medicine ; Medicine & Public Health ; Mental disorders ; Mental Disorders - diagnosis ; Mental Disorders - epidemiology ; Mental health ; Mental health care ; Mental health services ; Original Contribution ; Population studies ; Prospective Studies ; Psychiatry ; Psychopharmacology ; Remission ; Remission (Medicine) ; Stability ; Teenagers ; Young adults</subject><ispartof>European child & adolescent psychiatry, 2024-05, Vol.33 (5), p.1481-1494</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-7ec826b4d3f71336c0c235cda763b7c0ee955f6018d6211853775ab494fbc8f63</citedby><cites>FETCH-LOGICAL-c375t-7ec826b4d3f71336c0c235cda763b7c0ee955f6018d6211853775ab494fbc8f63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00787-023-02254-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00787-023-02254-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,30999,33774,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37422547$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Girela-Serrano, Braulio</creatorcontrib><creatorcontrib>Miguélez-Fernández, Carolina</creatorcontrib><creatorcontrib>Abascal-Peiró, Sofía</creatorcontrib><creatorcontrib>Peñuelas-Calvo, Inmaculada</creatorcontrib><creatorcontrib>Jiménez-Muñoz, Laura</creatorcontrib><creatorcontrib>Moreno, Manon</creatorcontrib><creatorcontrib>Delgado-Gómez, David</creatorcontrib><creatorcontrib>Bello, Hugo J.</creatorcontrib><creatorcontrib>Nicholls, Dasha</creatorcontrib><creatorcontrib>Baca-García, Enrique</creatorcontrib><creatorcontrib>Carballo, Juan José</creatorcontrib><creatorcontrib>Porras-Segovia, Alejandro</creatorcontrib><title>Diagnostic trajectories of mental disorders in children and adolescents: a cohort study</title><title>European child & adolescent psychiatry</title><addtitle>Eur Child Adolesc Psychiatry</addtitle><addtitle>Eur Child Adolesc Psychiatry</addtitle><description>Mental disorders in children and adolescents may follow different trajectories, such as remission, change of diagnosis, or addition of two or more comorbid diagnoses, showing a heterotypic pattern. This study aims to describe the main diagnostic trajectories across a broad range of mental disorder diagnostic categories, from childhood to adolescence and from adolescence to young adulthood in a clinical population. A prospective study was conducted among a clinical sample of children and adolescents who were aged 3–17 years at the face-to-face baseline interview. Electronic health records of these participants were reviewed 10 years later. The diagnostic stability over time was examined using the kappa coefficient, and factors associated with stability were explored using simple logistic regression. The study included a sample of 691 participants. The kappa coefficient for diagnostic stability across all diagnoses was 0.574 for the transition from childhood to adulthood, 0.614 from childhood to adolescence, and 0.733 from adolescence to adulthood. Neurodevelopmental diagnoses had the highest stability. Factors associated with higher diagnostic stability included family history of mental disorders, receiving psychopharmacological treatment, and symptom severity at baseline. We found a variable diagnostic stability across different diagnoses and age categories. The different life transitions represent complex periods that should not be overlooked from a clinical standpoint. An appropriate transition from child and adolescent mental health services to adult mental health services may have a positive impact on children and adolescents with mental disorders.</description><subject>Adolescent</subject><subject>Adolescents</subject><subject>Age differences</subject><subject>Child</subject><subject>Child & adolescent mental health</subject><subject>Child and Adolescent Psychiatry</subject><subject>Child development</subject><subject>Child, Preschool</subject><subject>Childhood</subject><subject>Children</subject><subject>Classification</subject><subject>Cohort analysis</subject><subject>Cohort Studies</subject><subject>Comorbidity</subject><subject>Computerized medical records</subject><subject>Electronic medical records</subject><subject>Female</subject><subject>Health records</subject><subject>Health services</subject><subject>Humans</subject><subject>Kappa coefficient</subject><subject>Life course</subject><subject>Life transitions</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Medical records</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mental disorders</subject><subject>Mental Disorders - diagnosis</subject><subject>Mental Disorders - epidemiology</subject><subject>Mental health</subject><subject>Mental health care</subject><subject>Mental health services</subject><subject>Original Contribution</subject><subject>Population studies</subject><subject>Prospective Studies</subject><subject>Psychiatry</subject><subject>Psychopharmacology</subject><subject>Remission</subject><subject>Remission (Medicine)</subject><subject>Stability</subject><subject>Teenagers</subject><subject>Young adults</subject><issn>1018-8827</issn><issn>1435-165X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>BHHNA</sourceid><recordid>eNp9kDtPwzAUhS0EoqXwBxiQJRaWgB_xI2yoPKVKLCDYLMd22lRpXOxk6L_HJQUkBobra8nfOff6AHCK0SVGSFzFdEiRIUJTEZZnaA-McU5Zhjl73093hGUmJREjcBTjEiHMCkQOwYiKfCsQY_B2W-t562NXG9gFvXSm86F2EfoKrlzb6QbaOvpgXYiwbqFZ1I0NroW6tVBb37hoEhavoYbGL3zoYOx6uzkGB5VuojvZ9Ql4vb97mT5ms-eHp-nNLDNUsC4TzkjCy9zSSmBKuUGGUGasFpyWwiDnCsYqnv5hOcFYMioE02Ve5FVpZMXpBFwMvuvgP3oXO7Wq00ZNo1vn-6iIpIyIgmOc0PM_6NL3oU3bKYoY4zkpZJ4oMlAm-BiDq9Q61CsdNgojtY1dDbGrFLv6il2hJDrbWfflytkfyXfOCaADENNTO3fhd_Y_tp_6AIzi</recordid><startdate>20240501</startdate><enddate>20240501</enddate><creator>Girela-Serrano, Braulio</creator><creator>Miguélez-Fernández, Carolina</creator><creator>Abascal-Peiró, Sofía</creator><creator>Peñuelas-Calvo, Inmaculada</creator><creator>Jiménez-Muñoz, Laura</creator><creator>Moreno, Manon</creator><creator>Delgado-Gómez, David</creator><creator>Bello, Hugo J.</creator><creator>Nicholls, Dasha</creator><creator>Baca-García, Enrique</creator><creator>Carballo, Juan José</creator><creator>Porras-Segovia, Alejandro</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7TK</scope><scope>7U3</scope><scope>BHHNA</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20240501</creationdate><title>Diagnostic trajectories of mental disorders in children and adolescents: a cohort study</title><author>Girela-Serrano, Braulio ; Miguélez-Fernández, Carolina ; Abascal-Peiró, Sofía ; Peñuelas-Calvo, Inmaculada ; Jiménez-Muñoz, Laura ; Moreno, Manon ; Delgado-Gómez, David ; Bello, Hugo J. ; Nicholls, Dasha ; Baca-García, Enrique ; Carballo, Juan José ; Porras-Segovia, Alejandro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-7ec826b4d3f71336c0c235cda763b7c0ee955f6018d6211853775ab494fbc8f63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adolescent</topic><topic>Adolescents</topic><topic>Age differences</topic><topic>Child</topic><topic>Child & adolescent mental health</topic><topic>Child and Adolescent Psychiatry</topic><topic>Child development</topic><topic>Child, Preschool</topic><topic>Childhood</topic><topic>Children</topic><topic>Classification</topic><topic>Cohort analysis</topic><topic>Cohort Studies</topic><topic>Comorbidity</topic><topic>Computerized medical records</topic><topic>Electronic medical records</topic><topic>Female</topic><topic>Health records</topic><topic>Health services</topic><topic>Humans</topic><topic>Kappa coefficient</topic><topic>Life course</topic><topic>Life transitions</topic><topic>Male</topic><topic>Medical diagnosis</topic><topic>Medical records</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mental disorders</topic><topic>Mental Disorders - diagnosis</topic><topic>Mental Disorders - epidemiology</topic><topic>Mental health</topic><topic>Mental health care</topic><topic>Mental health services</topic><topic>Original Contribution</topic><topic>Population studies</topic><topic>Prospective Studies</topic><topic>Psychiatry</topic><topic>Psychopharmacology</topic><topic>Remission</topic><topic>Remission (Medicine)</topic><topic>Stability</topic><topic>Teenagers</topic><topic>Young adults</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Girela-Serrano, Braulio</creatorcontrib><creatorcontrib>Miguélez-Fernández, Carolina</creatorcontrib><creatorcontrib>Abascal-Peiró, Sofía</creatorcontrib><creatorcontrib>Peñuelas-Calvo, Inmaculada</creatorcontrib><creatorcontrib>Jiménez-Muñoz, Laura</creatorcontrib><creatorcontrib>Moreno, Manon</creatorcontrib><creatorcontrib>Delgado-Gómez, David</creatorcontrib><creatorcontrib>Bello, Hugo J.</creatorcontrib><creatorcontrib>Nicholls, Dasha</creatorcontrib><creatorcontrib>Baca-García, Enrique</creatorcontrib><creatorcontrib>Carballo, Juan José</creatorcontrib><creatorcontrib>Porras-Segovia, Alejandro</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Neurosciences Abstracts</collection><collection>Social Services Abstracts</collection><collection>Sociological Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>European child & adolescent psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Girela-Serrano, Braulio</au><au>Miguélez-Fernández, Carolina</au><au>Abascal-Peiró, Sofía</au><au>Peñuelas-Calvo, Inmaculada</au><au>Jiménez-Muñoz, Laura</au><au>Moreno, Manon</au><au>Delgado-Gómez, David</au><au>Bello, Hugo J.</au><au>Nicholls, Dasha</au><au>Baca-García, Enrique</au><au>Carballo, Juan José</au><au>Porras-Segovia, Alejandro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnostic trajectories of mental disorders in children and adolescents: a cohort study</atitle><jtitle>European child & adolescent psychiatry</jtitle><stitle>Eur Child Adolesc Psychiatry</stitle><addtitle>Eur Child Adolesc Psychiatry</addtitle><date>2024-05-01</date><risdate>2024</risdate><volume>33</volume><issue>5</issue><spage>1481</spage><epage>1494</epage><pages>1481-1494</pages><issn>1018-8827</issn><eissn>1435-165X</eissn><abstract>Mental disorders in children and adolescents may follow different trajectories, such as remission, change of diagnosis, or addition of two or more comorbid diagnoses, showing a heterotypic pattern. This study aims to describe the main diagnostic trajectories across a broad range of mental disorder diagnostic categories, from childhood to adolescence and from adolescence to young adulthood in a clinical population. A prospective study was conducted among a clinical sample of children and adolescents who were aged 3–17 years at the face-to-face baseline interview. Electronic health records of these participants were reviewed 10 years later. The diagnostic stability over time was examined using the kappa coefficient, and factors associated with stability were explored using simple logistic regression. The study included a sample of 691 participants. The kappa coefficient for diagnostic stability across all diagnoses was 0.574 for the transition from childhood to adulthood, 0.614 from childhood to adolescence, and 0.733 from adolescence to adulthood. Neurodevelopmental diagnoses had the highest stability. Factors associated with higher diagnostic stability included family history of mental disorders, receiving psychopharmacological treatment, and symptom severity at baseline. We found a variable diagnostic stability across different diagnoses and age categories. The different life transitions represent complex periods that should not be overlooked from a clinical standpoint. An appropriate transition from child and adolescent mental health services to adult mental health services may have a positive impact on children and adolescents with mental disorders.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>37422547</pmid><doi>10.1007/s00787-023-02254-0</doi><tpages>14</tpages></addata></record> |
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| subjects | Adolescent Adolescents Age differences Child Child & adolescent mental health Child and Adolescent Psychiatry Child development Child, Preschool Childhood Children Classification Cohort analysis Cohort Studies Comorbidity Computerized medical records Electronic medical records Female Health records Health services Humans Kappa coefficient Life course Life transitions Male Medical diagnosis Medical records Medicine Medicine & Public Health Mental disorders Mental Disorders - diagnosis Mental Disorders - epidemiology Mental health Mental health care Mental health services Original Contribution Population studies Prospective Studies Psychiatry Psychopharmacology Remission Remission (Medicine) Stability Teenagers Young adults |
| title | Diagnostic trajectories of mental disorders in children and adolescents: a cohort study |
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