Small extracellular vesicles from HO-1-modified bone marrow-derived mesenchymal stem cells attenuate ischemia-reperfusion injury after steatotic liver transplantation by suppressing ferroptosis via miR-214-3p

Donor shortage is a major problem that limits liver transplantation availability. Steatotic donor liver presents a feasible strategy to solve this problem. However, severe ischemia-reperfusion injury (IRI) is an obstacle to the adoption of steatotic transplanted livers. Evidence from our prior studi...

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Veröffentlicht in:	Cellular signalling 2023-09, Vol.109, p.110793-110793, Article 110793
Hauptverfasser:	Zuo, Huaiwen, Wang, Yuxin, Yuan, Mengshu, Zheng, Weiping, Tian, Xiaorong, Pi, Yilin, Zhang, Xinru, Song, Hongli
Format:	Artikel
Sprache:	eng
Schlagworte:	BMMSCs Ferroptosis Ischemia-reperfusion injury Liver transplantation miR-214-3p Small extracellular vesicles Steatotic donor liver
Online-Zugang:	Volltext
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