Feasibility analysis of rapid gene detection using intraoperative frozen tissues: comparison of intraoperative frozen tissues with paraffin-embedded tissues in epidermal growth factor receptor gene mutation detection of lung adenocarcinoma

Background Epidermal growth factor receptor (EGFR) is the driver gene with the highest frequency of mutations in lung adenocarcinoma and can guide the development of targeted therapies. The detection of routine gene mutations must be performed after the preparation of paraffin samples in a standard...

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Veröffentlicht in:Journal of cancer research and clinical oncology 2023-10, Vol.149 (13), p.12025-12032
Hauptverfasser: Zhang, Juan-juan, Long, Zheng-bo, Luo, Li-lin, Li, Lin-Hui, Yang, Hui, Cao, Yue, Wang, Li, Wang, Wan-pu
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Sprache:eng
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