Attenuative effect of astilbin on polystyrene microplastics induced testicular damage: Biochemical, spermatological and histopathological-based evidences

Polystyrene microplastics (PS-MPs) are the potential environmental pollutants that possess the ability to induce testicular damage. Astilbin (ASB) is a dihydroflavonol, abundantly reported in multiple plants that has various pharmacological properties. This research elucidated the mitigative potenti...

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Veröffentlicht in:	Toxicology and applied pharmacology 2023-07, Vol.471, p.116559-116559, Article 116559
Hauptverfasser:	Rizwan, Arooj, Ijaz, Muhammad Umar, Hamza, Ali, Anwar, Haseeb
Format:	Artikel
Sprache:	eng
Schlagworte:	adults Animals Antioxidant antioxidants Antioxidants - pharmacology apoptosis Astilbin caspase-3 catalase epididymis follicle-stimulating hormone glutathione peroxidase glutathione-disulfide reductase histology histopathology interleukin-6 luteinizing hormone Male males microplastics Microplastics - metabolism Microplastics - pharmacology necrosis neoplasms Oxidative Stress pharmacology Plastics - metabolism poisoning Polystyrene Microplastics polystyrenes Polystyrenes - metabolism Polystyrenes - toxicity prostaglandin synthase Rats Rats, Wistar Semen - metabolism spermatozoa superoxide dismutase testes Testicular Damage Testis testosterone toxicity viability
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