Initiation of fatty acid biosynthesis in Pseudomonas putida KT2440

Deciphering the mechanisms of bacterial fatty acid biosynthesis is crucial for both the engineering of bacterial hosts to produce fatty acid-derived molecules and the development of new antibiotics. However, gaps in our understanding of the initiation of fatty acid biosynthesis remain. Here, we demo...

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Veröffentlicht in:	Metabolic engineering 2023-03, Vol.76, p.193-203
Hauptverfasser:	McNaught, Kevin J., Kuatsjah, Eugene, Zahn, Michael, Prates, Érica T., Shao, Huiling, Bentley, Gayle J., Pickford, Andrew R., Gruber, Josephine N., Hestmark, Kelley V., Jacobson, Daniel A., Poirier, Brenton C., Ling, Chen, San Marchi, Myrsini, Michener, William E., Nicora, Carrie D., Sanders, Jacob N., Szostkiewicz, Caralyn J., Veličković, Dušan, Zhou, Mowei, Munoz, Nathalie, Kim, Young-Mo, Magnuson, Jon K., Burnum-Johnson, Kristin E., Houk, K.N., McGeehan, John E., Johnson, Christopher W., Beckham, Gregg T.
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Oxoacyl-(Acyl-Carrier-Protein) Synthase - genetics biosynthesis biotechnology Decarboxylase decarboxylation enzymes Fatty acid biosynthesis Fatty Acids Hotdog fold Mutagenesis Pseudomonas putida Pseudomonas putida - genetics Pseudomonas putida - metabolism X-ray diffraction
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