Online protein unfolding characterized by ion mobility electron capture dissociation mass spectrometry: cytochrome C from neutral and acidic solutions

Electrospray ionization mass spectrometry (ESI-MS) experiments, including ion mobility spectrometry mass spectrometry (ESI-IMS-MS) and electron capture dissociation (ECD) of proteins ionized from aqueous solutions, have been used for the study of solution-like structures of intact proteins. By mixin...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2023-02, Vol.415 (5), p.749-758
Hauptverfasser:	Cain, Rebecca L., Webb, Ian K.
Format:	Artikel
Sprache:	eng
Schlagworte:	ABC Highlights: authored by Rising Stars and Top Experts Acids Analysis Analytical Chemistry Aqueous solutions Beta decay Biochemistry Capture Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Cytochrome Cytochrome c Cytochromes Cytochromes c - chemistry Denaturation dissociation Electron capture Electrons electrospray ionization mass spectrometry energy Folding Food Science Intermediates Ion Mobility Spectrometry Ionic mobility Ionization Ions Ions - chemistry Laboratory Medicine Mass spectrometry Mass spectroscopy Methods Mobility Monitoring/Environmental Analysis Paper in Forefront Protein folding Protein Unfolding Proteins Proteins - chemistry Scientific imaging Spectrometry, Mass, Electrospray Ionization - methods Spectroscopy Water
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