Combining PD-L1 blockade with immunogenic cell death induced by AIE photosensitizer to improve antitumor immunity

Immunogenic cell death (ICD) is considered an effective death mode to trigger immune response. However, the currently available efficient ICD inducers are quite limited. Endoplasmic reticulum (ER) stress is known as the precursor of ICD, which can be directly triggered by reactive oxygen species in...

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Veröffentlicht in:	Biomaterials 2022-12, Vol.291, p.121899-121899, Article 121899
Hauptverfasser:	Li, Jianqing, Dai, Jun, Zhuang, Zeyan, Meng, Zijuan, Hu, Jing-Jing, Lou, Xiaoding, Xia, Fan, Zhao, Zujin, Tang, Ben Zhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggregation-induced emission antineoplastic activity biocompatible materials cell death Cell Line, Tumor death endoplasmic reticulum Endoplasmic reticulum stress Immune checkpoint blockade immune response Immunogenic Cell Death Immunotherapy irradiation metastasis neoplasms Photochemotherapy Photodynamic therapy photosensitizing agents Photosensitizing Agents - pharmacology Photosensitizing Agents - therapeutic use reactive oxygen species synergism white light
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