The characterization of the sensitive ovarian cancer cell lines A2780 and W1 in response to ovarian CAFs

The cancer-associated fibroblasts (CAFs) are one of the most abundant components of the tumor microenvironment (TME). CAFs have been implicated in tumor progression, extracellular matrix (ECM) remodeling, and treatment resistance. Drug resistance is the primary limiting factor in achieving cures for...

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Veröffentlicht in:	Biochemical and biophysical research communications 2023-06, Vol.662, p.1-7
Hauptverfasser:	Wojtowicz, Karolina, Nowicki, Michał
Format:	Artikel
Sprache:	eng
Schlagworte:	CAFs Cancer associated fibroblast cancer therapy Cancer-Associated Fibroblasts - metabolism Cell Line, Tumor cell structures coculture Coculture Techniques Drug resistance drugs extracellular matrix Female fibroblasts fibronectins Humans neoplasm cells neoplasm progression Ovarian cancer cell lines ovarian neoplasms Ovarian Neoplasms - drug therapy Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Tumor Microenvironment - genetics Western blotting
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