Simultaneous voltammetric determination of 7-methyl-guanine and 5-methyl-cytosine using a cathodically pre-treated boron-doped diamond electrode

Given the importance of identifying the presence of biomarkers of human diseases in DNA samples, the main objective of this work was to investigate, for the first time, the electro-catalytic oxidation of 7-methyl-guanine (7-mGua) and 5-methyl-cytosine (5-mCyt) on a boron doped diamond electrode pre-...

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Veröffentlicht in:	Analytical biochemistry 2023-06, Vol.671, p.115135-115135, Article 115135
Hauptverfasser:	Oliveira, José Eudes S., Araújo, Alex P., Alves, Arthur S., Silva, Maycom W.F., Almeida, João Paulo B. de, Nascimento, José Ailton M., dos Santos, Vagner B., Oliveira, Severino Carlos B.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Methyl-cytosine 5-Methylcytosine 7-Methyl-guanine biomarkers Boron Boron doped diamond electrode detection limit DNA DNA-Methylation Electrochemical methods Electrodes electrolytes Guanine Humans Methylated DNA adducts oxidation Oxidation-Reduction species voltammetry
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