MIR-107/HMGB1/FGF-2 axis responds to excessive mechanical stretch to promote rapid repair of vascular endothelial cells

The increase of vascular wall tension can lead to endothelial injury during hypertension, but its potential mechanism remains to be studied. Our results of previous study showed that HUVECs could induce changes in HMGB1/RAGE to resist abnormal mechanical environments in pathological mechanical stret...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2023-08, Vol.744, p.109686-109686, Article 109686
Hauptverfasser:	Ma, Haiyang, Wang, Li, Sun, Haoyu, Yu, Qing, Yang, Tiantian, Wang, Yajing, Niu, Bin, Jia, Yaru, Liu, Yang, Liang, Ziwei, An, Meiwen, Guo, Jiqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Fibroblast growth factor 2 High-mobility group box1 Human umbilical vein endothelial cells Hypertension Mechanical stretching MicroRNA-107
Online-Zugang:	Volltext
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