Cryo-EM structures of actin binding proteins as tool for drug discovery

[Display omitted] Cellular actin dynamic is controlled by a plethora of actin binding proteins (ABPs), including actin nucleating, bundling, cross-linking, capping, and severing proteins. In this review, regulation of actin dynamics by ABPs will be introduced, and the role of the F-actin severing pr...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemical pharmacology 2023-08, Vol.214, p.115680-115680, Article 115680
Hauptverfasser:	Dahlstroem, Christian, Paraschiakos, Themistoklis, Sun, Han, Windhorst, Sabine
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cancer Cryo-EM Cytoskeleton Drug design Metastasis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!