The Endogenous Retinoic Acid Receptor Pathway Is Exploited by Mycobacterium tuberculosis during Infection, Both In Vitro and In Vivo

Retinoic acid (RA) is a fundamental vitamin A metabolite involved in regulating immune responses through the nuclear RA receptor (RAR) and retinoid X receptor. While performing experiments using THP-1 cells as a model for Mycobacterium tuberculosis infection, we observed that serum-supplemented cult...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of immunology (1950) 2023-08, Vol.211 (4), p.601-611
Hauptverfasser:	Tenório de Menezes, Yonne Karoline, Eto, Carolina, de Oliveira, Joseana, Larson, Erica C, Mendes, Daniel A G B, Dias, Greicy Brisa Malaquias, Delgobo, Murilo, Gubernat, Abigail K, Gleim, Janelle L, Munari, Eduarda Laís, Starick, Marick, Ferreira, Fabienne, Mansur, Daniel Santos, Costa, Diego L, Scanga, Charles A, Báfica, André
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drug Inverse Agonism Humans Mice Mycobacterium tuberculosis - metabolism Receptors, Retinoic Acid - metabolism Retinoid X Receptors Tretinoin - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!