Serum NfL and GFAP are associated with incident dementia and dementia mortality in older adults: The cardiovascular health study

INTRODUCTION Circulating neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) have been independently associated with dementia risk. Their additive association, and their associations with dementia‐specific mortality, have not been investigated. METHODS We associated serum NfL,...

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Veröffentlicht in:	Alzheimer's & dementia 2023-12, Vol.19 (12), p.5672-5680
Hauptverfasser:	Cronjé, Héléne T., Liu, Xiaojuan, Odden, Michelle C., Moseholm, Kristine F., Seshadri, Sudha, Satizabal, Claudia L., Lopez, Oscar L., Bis, Joshua C., Djoussé, Luc, Fohner, Alison E., Psaty, Bruce M., Tracy, Russell P., Longstreth, W. T, Jensen, Majken K., Mukamal, Kenneth J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biomarkers blood‐based biomarkers cognition Cognitive Dysfunction - epidemiology dementia Dementia - epidemiology Glial Fibrillary Acidic Protein Humans Intermediate Filaments longitudinal Modified Mini‐Mental State Examination mortality risk factor serum
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