Physical training promotes remodeling of the skeletal muscle extracellular matrix: An ultrastructural study in a murine model of Down syndrome

Down syndrome (DS) is a genetically based disease caused by triplication of chromosome 21. DS is characterized by multi-systemic premature aging associated with deficit in motor coordination, balance, and postural control. Using a morphological, morphometrical, and immunocytochemical ultrastructural...

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Veröffentlicht in:	Microscopy research and technique 2023-11, Vol.86 (11), p.1517-1528
Hauptverfasser:	Cisterna, Barbara, Boschi, Federico, Lacavalla, Maria Assunta, Vattemi, Gaetano Nicola Alfio, Zancanaro, Carlo, Malatesta, Manuela
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animal models Anomalies Chromosome 21 Collagen Coordination Density Down syndrome Down's syndrome Extracellular matrix Fibrils Hypertrophy Morphometry Muscles Musculoskeletal system Myofibrils Physical training Skeletal muscle Trisomy
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