Paternal low-dose benzo(a)pyrene exposure in rats impairs sexual development and fertility of the paternal lineage in F2 generation: A transgenerational study

The field of Paternal Origins of Health and Disease (POHaD) is highly relevant but remains under-explored. The F2 generation from males indirectly exposed (F1 - via germ cells) to benzo(a)pyrene (BaP), named PF2, was investigated in this study under parameters of sexual development and reproductive...

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Veröffentlicht in:	Toxicology (Amsterdam) 2023-08, Vol.494, p.153585-153585, Article 153585
Hauptverfasser:	Jorge, Bárbara Campos, Stein, Julia, Reis, Ana Carolina Casali, Bueno, Jéssica Nogueira, Paschoalini, Beatriz Rizzo, Moreira, Suyane da Silva, Manoel, Beatriz de Matos, Arena, Arielle Cristina
Format:	Artikel
Sprache:	eng
Schlagworte:	Endocrine disrupting Paternal origins of health and disease Reproductive toxicity Transgenerational inheritance
Online-Zugang:	Volltext
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