“Are we barking up the wrong tree? Too much emphasis on Cutibacterium acnes and ignoring other pathogens”— a study based on next-generation sequencing of normal and diseased discs

The majority of literature on bacterial flora in the disc stands disadvantaged in utilizing traditional culture methods and targeting a single bacterium, Cutibacterium acnes. Our objective was to document the diversity in the bacterial flora between normal and degenerated discs for shortlisting pote...

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Veröffentlicht in:	The spine journal 2023-10, Vol.23 (10), p.1414-1426
Hauptverfasser:	Rajasekaran, Shanmuganathan, Vasudevan, Gowdaman, Easwaran, Murugesh, Devi Ps, Narmatha, Anand K S, Sri Vijay, Muthurajan, Raveendran, Tangavel, Chitraa, Murugan, Chandhan, B T, Pushpa, Shetty, Ajoy Prasad, Kanna, Rishi Mugesh
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial metabolites C. acnes Disc degeneration Dysbiosis Metabolomics Microbiome Modic changes Next-generation sequencing Quorum sensing
Online-Zugang:	Volltext
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