Antiprotozoal activity of auranofin on Trypanosoma cruzi, Leishmania tropica and Toxoplasma gondii: in vitro and ex vivo study

ABSTRACT Background Three obligate intracellular protozoan parasite species, which are responsible for significant morbidity and mortality and settle in macrophage cells, affect more than one-half of the world's population, namely, Trypanosoma cruzi, Leishmania tropica and Toxoplasma gondii, wh...

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Veröffentlicht in:	Transactions of the Royal Society of Tropical Medicine and Hygiene 2023-10, Vol.117 (10), p.733-740
Hauptverfasser:	Yıldırım, Ahmet, Özbilgin, Ahmet, Yereli, Kor
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiprotozoal Agents - pharmacology Antiprotozoal Agents - therapeutic use Auranofin - pharmacology Auranofin - therapeutic use Chagas Disease - parasitology Chlorocebus aethiops Humans Leishmania tropica Leishmaniasis Toxoplasma Toxoplasmosis Trypanosoma cruzi Vero Cells
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