Activatable Mn2+-Armed nanoagonist augments antitumor immunity in colorectal cancer: A NIR-II Photonic neoadjuvant paradigm

Postoperative recurrence frequently occurs in patients with colorectal cancer (CRC) due to residual microtumors and host cellular immune dysfunction, leading to major setbacks in clinical outcomes and CRC staging. As an increasingly prevalent therapeutic option for CRC patients, neoadjuvant chemorad...

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Veröffentlicht in:	Biomaterials 2023-09, Vol.300, p.122206-122206, Article 122206
Hauptverfasser:	Liang, Qing, Chen, Jiayuan, Hou, Shuai, Li, Di, Zhu, Ying, Li, Ruiqi, Chen, Lian, Li, Jiao, Fu, Wei, Lei, Shiqiong, Zhang, Biying, Zheng, Xin, Zhang, Tao, Duan, Hongwei, He, Wenshan, Ren, Jinghua
Format:	Artikel
Sprache:	eng
Schlagworte:	cGAS/STING pathway Immunogenic cell death Manganese ions Nanoagonist Neoadjuvant therapy Second near-infrared window
Online-Zugang:	Volltext
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