Syntaxin4, P-cadherin, and CCAAT enhancer binding protein β as signaling elements in the novel differentiation pathway for cultured embryonic stem cells

Pluripotent stem cells possess the potential to differentiate into all three germ layers. However, upon removal of the stemness factors, pluripotent stem cells, such as embryonic stem cells (ESCs), exhibit EMT-like cell behavior and lose stemness signatures. This process involves the membrane transl...

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Veröffentlicht in:	Biochemical and biophysical research communications 2023-09, Vol.672, p.27-35
Hauptverfasser:	Matsuguchi, Shuji, Hirai, Yohei
Format:	Artikel
Sprache:	eng
Schlagworte:	Brachyury Cadherins - metabolism CCAAT-Enhancer-Binding Protein-beta - metabolism Cell Differentiation - physiology Cells, Cultured Embryonic stem cell Embryonic Stem Cells Gastrulation Mesoderm induction Pluripotent Stem Cells α−smooth muscle actin
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