Norisoboldine exerts antiallergic effects on IgE/ovalbumin-induced allergic asthma and attenuates FcεRI-mediated mast cell activation

[Display omitted] •NOR reduces IgE production and airway hyperresponsiveness in asthmatic mice.•NOR treatment attenuates airway inflammation in asthmatic mice.•NOR inhibits inflammatory mediator release by IgE/OVA-activated mast cells.•NOR suppresses the FcεRI-mediated JNK signaling pathway in mast...

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Veröffentlicht in:	International immunopharmacology 2023-08, Vol.121, p.110473-110473, Article 110473
Hauptverfasser:	Chang, Jer-Hwa, Chuang, Hsiao-Chi, Fan, Chia-Kwung, Hou, Tsung-Yun, Chang, Yu-Cheng, Lee, Yueh-Lun
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic asthma Immunoglobulin E Mast cell Norisoboldine
Online-Zugang:	Volltext
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