A 5-Minute Delay From Bolus Injection to Infusion Halves Plasma Concentration of Tissue Plasminogen Activator

Reducing the time between onset of cerebral infarction and treatment with tissue plasminogen activator improves the prognosis of patients with cerebral infarction. Diverse dosing protocols have been developed with the aim of reducing the time to bolus injection; however, only a few studies have inve...

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Veröffentlicht in:	The Journal of emergency medicine 2023-06, Vol.64 (6), p.709-713
Hauptverfasser:	Kobayashi, Yuya, Saito, Takuya, Kawabata, Yuichi, Igari, Takako, Kondo, Yasufumi, Yamamoto, Kanji, Sekijima, Yoshiki
Format:	Artikel
Sprache:	eng
Schlagworte:	alteplase cerebral infarction Cerebral Infarction - drug therapy delay Fibrinolytic Agents - pharmacology Fibrinolytic Agents - therapeutic use Humans Infusions, Intravenous Injections, Intravenous interruption Recombinant Proteins Thrombolytic Therapy tissue plasminogen activator Tissue Plasminogen Activator - pharmacology Tissue Plasminogen Activator - therapeutic use
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