Efficient production of 2-keto-L-gulonic acid from D-glucose in Gluconobacter oxydans ATCC9937 by mining key enzyme and transporter

[Display omitted] •Gluconobacter oxydans ATCC9937 can synthesize 2-KLG from D-glucose.•A 2,5-DKG reductase with stronger activity has been obtained from G. oxydans.•A functional 2,5-DKG transporter KgtpA has been identified from Tatumella citrea.•The highest 2-KLG titer synthesized from D-glucose ha...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Bioresource technology 2023-09, Vol.384, p.129316-129316, Article 129316
Hauptverfasser:	Li, Guang, Li, Dong, Zeng, Weizhu, Qin, Zhijie, Chen, Jian, Zhou, Jingwen
Format:	Artikel
Sprache:	eng
Schlagworte:	2,5-diketo-D-glucose 2,5-DKG reductase 2,5-DKG transporter 2-keto-L-gulonic acid Ascorbic Acid Fermentation Gluconobacter oxydans Gluconobacter oxydans - metabolism Glucose - metabolism Sugar Acids - metabolism vitamin C
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!