Enhanced acetate utilization for value-added chemicals production in Yarrowia lipolytica by integration of metabolic engineering and microbial electrosynthesis

The limited supply of reducing power restricts the efficient utilization of acetate in Yarrowia lipolytica. Here, microbial electrosynthesis (MES) system, enabling direct conversion of inward electrons to NAD(P)H, was used to improve the production of fatty alcohols from acetate based on pathway eng...

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Veröffentlicht in:	Biotechnology and bioengineering 2023-10, Vol.120 (10), p.3013-3024
Hauptverfasser:	Huang, Congcong, Chen, Yaru, Cheng, Shuai, Li, Mengxu, Wang, Luxin, Cheng, Meijie, Li, Feng, Cao, Yingxiu, Song, Hao
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Alcohols Betulinic acid Carbon sources Direct conversion Dry cells Gene expression Metabolic engineering Microorganisms Pentose Pentose phosphate pathway Synthesis Yarrowia lipolytica
Online-Zugang:	Volltext
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