RISING STARS: Liver sinusoidal endothelial transcription factors in metabolic homeostasis and disease

Liver sinusoidal endothelial cells (LSECs) are highly specialised endothelial cells that form the liver microvasculature. LSECs maintain liver homeostasis, scavenging bloodborne molecules, regulating immune response, and actively promoting hepatic stellate cell quiescence. These diverse functions ar...

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Veröffentlicht in:	Journal of molecular endocrinology 2023-08, Vol.71 (2), p.1
Hauptverfasser:	Nagy, Dorka, Maude, Hannah, Birdsey, Graeme M, Randi, Anna M, Cebola, Inês
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Blood vessels Endothelial cells Endothelial Cells - metabolism Fatty liver Hepatocytes Homeostasis Humans Immune response Liver - metabolism Liver diseases Metabolic syndrome Metabolism Microvasculature Non-alcoholic Fatty Liver Disease - etiology Transcription factors Transcription Factors - metabolism Transcriptomes
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