Optimizing the safety of antibody–drug conjugates for patients with solid tumours

Over the past 5 years, improvements in the design of antibody–drug conjugates (ADCs) have enabled major advances that have reshaped the treatment of several advanced-stage solid tumours. Considering the intended rationale behind the design of ADCs, which is to achieve targeted delivery of cytotoxic...

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Veröffentlicht in:Nature reviews. Clinical oncology 2023-08, Vol.20 (8), p.558-576
Hauptverfasser: Tarantino, Paolo, Ricciuti, Biagio, Pradhan, Shan M., Tolaney, Sara M.
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Sprache:eng
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