CIARA: a cluster-independent algorithm for identifying markers of rare cell types from single-cell sequencing data

A powerful feature of single-cell genomics is the possibility to identify cell types from their molecular profiles. In particular, identifying novel rare cell types and their marker genes is a key potential of single-cell RNA-sequencing. Standard clustering approaches perform well in identifying rel...

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Veröffentlicht in:Development (Cambridge) 2023-06, Vol.150 (11)
Hauptverfasser: Lubatti, Gabriele, Stock, Marco, Iturbide, Ane, Ruiz Tejada Segura, Mayra L, Riepl, Melina, Tyser, Richard C V, Danese, Anna, Colomé-Tatché, Maria, Theis, Fabian J, Srinivas, Shankar, Torres-Padilla, Maria-Elena, Scialdone, Antonio
Format: Artikel
Sprache:eng
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