Iron-Catalyzed Oxidative Cyclization of 2‑Amino Styrenes with Alcohols and Methyl Arenes for the Synthesis of Polysubstituted Quinolines

Herein, we present the iron-catalyzed oxidative cyclization of alcohol/methyl arene with 2-amino styrene to synthesize polysubstituted quinoline. Low-oxidation level substrates such as alcohols and methyl arenes are converted to aldehydes in the presence of an iron catalyst and di-t-butyl peroxide....

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Veröffentlicht in:	Journal of organic chemistry 2023-07, Vol.88 (13), p.8099-8113
Hauptverfasser:	Lee, Seok Beom, Chun, Simin, Choi, Seung Hyun, Hong, Junhwa, Oh, Dong-Chan, Hong, Suckchang
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohols Catalysis Cyclization Iron Oxidative Stress Quinolines Styrenes
Online-Zugang:	Volltext
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