D-A-D-T-type four-component radical dual-difunctionalization and acylative azidation of two different alkenes

From a single alkene to two different alkenes! An iron-catalyzed four-component reaction involving an aldehyde, two different alkenes and TMSN 3 is developed to assemble these four reactants in an orderly fashion based on the inherent nucleophilic/electrophilic reaction activity of the radicals and...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2023-06, Vol.59 (51), p.7986-7989
Hauptverfasser: Liu, Ren-Xiang, Chen, Xin, Yang, Luo
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Chen, Xin
Yang, Luo
description From a single alkene to two different alkenes! An iron-catalyzed four-component reaction involving an aldehyde, two different alkenes and TMSN 3 is developed to assemble these four reactants in an orderly fashion based on the inherent nucleophilic/electrophilic reaction activity of the radicals and alkenes via a double radical addition, providing various multifunctional compounds containing an azido group and two carbonyl groups. From a single alkene to two different alkenes! An iron-catalyzed four-component reaction of aldehydes, two different alkenes and TMSN 3 is developed to orderly assemble these four reactants according to their inherent nucleo/electrophilic activity.
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source Royal Society Of Chemistry Journals; Alma/SFX Local Collection
subjects Aldehydes
Alkenes
Carbonyl groups
Carbonyls
title D-A-D-T-type four-component radical dual-difunctionalization and acylative azidation of two different alkenes
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