NEAT1_2/RRAD/EHF Positive Feedback Loop Facilitates Aerobic Glycolysis in Papillary Thyroid Cancer Cells

Abstract Papillary thyroid carcinoma (PTC) is the most prevalent endocrine-related malignancy. In spite of the good prognosis, a more aggressive disease can develop in some PTC patients, leading to poor survival. Nuclear paraspeckle assembly transcript 1 (NEAT1) enhances tumorigenesis; however, the...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2023-07, Vol.164 (7), p.1
Hauptverfasser:	Sun, Wei, Wang, Zhiyuan, Qin, Yuan, Ji, Xiaoyu, Huang, Jiapeng, Zhang, Fan, Wang, Zhihong, Dong, Wenwu, He, Liang, Zhang, Hao
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cell Line, Tumor Cell Proliferation - genetics Chromatin Diabetes mellitus Diabetes Mellitus - genetics Endocrinology Feedback Feedback loops Gene Expression Regulation, Neoplastic Glucose metabolism Glycolysis Glycolysis - genetics Hexokinase Humans Immunocytochemistry Immunoprecipitation Kinases Malignancy Medical prognosis MicroRNAs - genetics Papillary thyroid cancer Papillary thyroid carcinoma Polymerase chain reaction Positive feedback Prognosis Protein binding Pyruvate kinase Pyruvic acid Reverse transcription RNA RNA, Long Noncoding - metabolism RNA-binding protein Thyroid Thyroid cancer Thyroid Cancer, Papillary - metabolism Thyroid gland Thyroid Neoplasms - pathology Transcription Factors - metabolism Tumorigenesis
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