Mitigating neutrophil trafficking and cardiotoxicity with DS-IkL in a microphysiological system of a cytokine storm

A feature of severe COVID-19 is the onset of an acute and intense systemic inflammatory response referred to as the "cytokine storm". The cytokine storm is characterized by high serum levels of inflammatory cytokines and the subsequent transport of inflammatory cells to damaging levels in...

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Veröffentlicht in:	Lab on a chip 2023-06, Vol.23 (13), p.35-361
Hauptverfasser:	Shirure, Venktesh S, Yechikov, Sergey, Shergill, Bhupinder S, Dehghani, Tima, Block, Anton V, Sodhi, Harkanwalpreet, Panitch, Alyssa, George, Steven C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioaccumulation Carbohydrates Cardiotoxicity COVID-19 Cytokine storm Cytokines Endothelial Cells Infiltration Inflammatory response Leukocytes Mice Microphysiological Systems Myocardium Neutrophils Temporal resolution
Online-Zugang:	Volltext
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