A new approach methodology using kinetically-derived maximum dose levels in risk assessment – A case study with afidopyropen

We present a case study for afidopyropen (AF; insecticide) to characterize chronic dietary human health risk using a Risk 21-based approach. Our objective is to use a well-tested pesticidal active ingredient (AF) to show how a new approach methodology (NAM), using the kinetically-derived maximum dos...

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Veröffentlicht in:	Regulatory toxicology and pharmacology 2023-08, Vol.142, p.105429-105429, Article 105429
Hauptverfasser:	Loccisano, Anne E., Freeman, Elaine, Doi, Adriana, Frericks, Markus, Fegert, Ivana, Fabian, Eric, Riffle, Brandy
Format:	Artikel
Sprache:	eng
Schlagworte:	Agrochemicals Animals Heterocyclic Compounds, 4 or More Rings Human health risk assessment Humans Kinetically derived maximum dose Lactones New approach methodology Pesticides - toxicity Rats Risk Assessment - methods
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