Delivery of low-density lipoprotein from endocytic carriers to mitochondria supports steroidogenesis

The low-density lipoprotein (LDL) is a major cholesterol carrier in circulation and is internalized into cells through LDL receptor (LDLR)-mediated endocytosis. The LDLR protein is highly expressed in the steroidogenic organs and LDL cholesterol is an important source for steroidogenesis. Cholestero...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature cell biology 2023-07, Vol.25 (7), p.937-949
Hauptverfasser:	Zhou, Yu-Xia, Wei, Jian, Deng, Gang, Hu, Ao, Sun, Pu-Yu, Zhao, Xiaolu, Song, Bao-Liang, Luo, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/109 13/51 13/89 14/19 14/28 14/35 38/22 38/23 38/47 38/77 38/90 631/45/287 631/80/313 82/80 Biomedical and Life Sciences Biosynthesis Cancer Research Cardiolipin Cell Biology Cholesterol Density Developmental Biology Endocytosis Genetic screening Genomes Intracellular LDLR protein Life Sciences Lipids Low density lipoprotein Low density lipoprotein receptors Lysosomes Membrane fusion Membrane proteins Membrane vesicles Membranes Mitochondria Phosphatidic acid Proteins Receptor density Receptors Stem Cells Steroidogenesis Steroids Vesicle fusion Vesicles
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!