Features of Isoforms of Human Soluble TACI

The BAFF/APRIL-system with the two cytokines BAFF and APRIL and their three receptors, transmembrane activator and CAML interactor (TACI), BAFF receptor, and B-cell maturation Ag, is important for B cell maintenance. The BAFF/APRIL system is a therapeutic target in B cell-derived malignancies and au...

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Veröffentlicht in:	The Journal of immunology (1950) 2023-07, Vol.211 (2), p.199-208
Hauptverfasser:	Fichtner, Miriam L, Rübsamen, Heike, Smolle, Michaela, Schaller, Jonas, Feederle, Regina, Bültmann, Andreas, Kümpfel, Tania, Schneider, Pascal, Thaler, Franziska S, Meinl, Edgar
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing B-Cell Activating Factor - metabolism B-Cell Activation Factor Receptor - genetics B-Lymphocytes Cytokines - genetics Humans Protein Isoforms - genetics Transmembrane Activator and CAML Interactor Protein - genetics Tumor Necrosis Factor Ligand Superfamily Member 13 - genetics Tumor Necrosis Factor Ligand Superfamily Member 13 - metabolism
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