Circ-100290 Regulates Autophagy-Mediated Angiogenesis of Human Umbilical Vein Endothelial Cells Induced by Conditioned Medium of Human Amniotic Mesenchymal Stem Cells

Conditioned medium (CM) from human amnion-derived mesenchymal stem cells (hAMSCs) exhibits excellent pro-angiogenic capacity, and circ-100290 participates in this process. Autophagy is involved in the relevant mechanisms of angiogenesis, but it is unclear whether autophagy is related to the pro-angi...

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Veröffentlicht in:	Discovery medicine 2023-06, Vol.35 (176), p.383-393
Hauptverfasser:	Yang, Leiting, Yan, Han, Liang, Yi, Sun, Dian, Lu, Shijun, Tang, Zichun, Ma, Ming, Shen, Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Amnion - metabolism Autophagy Beclin-1 - genetics Beclin-1 - metabolism Beclin-1 - pharmacology Culture Media, Conditioned - metabolism Culture Media, Conditioned - pharmacology Human Umbilical Vein Endothelial Cells - metabolism Humans Matrix Metalloproteinase 2 - metabolism Mesenchymal Stem Cells - metabolism Neovascularization, Physiologic Vascular Endothelial Growth Factor A
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