A Phase I Study of Ex Vivo Expanded Allogeneic Bone Marrow–Derived Mesenchymal Stem Cells for the Treatment of Pediatric Perianal Fistulizing Crohn’s Disease

Abstract Background Perianal fistulizing Crohn’s disease is notoriously difficult to treat. Recent studies of mesenchymal stem cells have demonstrated safety and efficacy of this novel treatment approach. However, no studies to date have included pediatric patients. We sought to determine safety and...

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Veröffentlicht in:Inflammatory bowel diseases 2023-12, Vol.29 (12), p.1912-1919
Hauptverfasser: Lightner, Amy L, Otero-Pineiro, Ana, Reese, Jane, Ream, Justin, Nachand, Douglas, Adams, Ashley C, VanDenBossche, Alexandra, Kurowski, Jacob A
Format: Artikel
Sprache:eng
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