Comparative Genomic Analysis of Pancreatic Acinar Cell Carcinoma (PACC) and Pancreatic Ductal Adenocarcinoma (PDAC) Unveils New Actionable Genomic Aberrations in PACC

Pure pancreatic acinar cell carcinomas (PACC) are rare malignancies with no established treatment. PACC demonstrates significant genetic intertumoral heterogeneity with multiple pathways involved, suggesting using targeted cancer therapeutics to treat this disease. We aggregated one of the largest d...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Clinical cancer research 2023-09, Vol.29 (17), p.3408-3417
Hauptverfasser:	Florou, Vaia, Elliott, Andrew, Bailey, Matthew H, Stone, David, Affolter, Kajsa, Soares, Heloisa P, Nevala-Plagemann, Chris, Scaife, Courtney, Walker, Phillip, Korn, W Michael, Lou, Emil, Shroff, Rachna T, Hosein, Peter J, Garrido-Laguna, Ignacio
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Acinar Cell - genetics Carcinoma, Acinar Cell - pathology Carcinoma, Pancreatic Ductal - drug therapy Carcinoma, Pancreatic Ductal - genetics Genomics Humans Mutation Pancreatic Neoplasms - drug therapy Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Precision Medicine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!