Palladium/Norbornene Cooperative-Catalyzed Cascade Decarboxylative Cyclization of 4‑Iodoisoquinolin-1(2H)‑ones with o‑Bromobenzoic Acids: Access to Diverse Fused Phenanthridinones and Hepta[1,2‑c]isoquinolinones

A novel three-component Pd/norbornene cooperative catalysis cascade decarboxylative [2+2+2]/[2+2+3]­cyclization of 4-iodoisoquinolin-1­(2H)-ones and o-bromobenzoic acids or 8-bromo-1-naphthoic acid has been developed. The method affords a range of fused phenanthridinones and hepta­[1,2-c]­isoquinoli...

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Veröffentlicht in:	Journal of organic chemistry 2023-07, Vol.88 (13), p.8329-8344
Hauptverfasser:	Huang, Xiao-Hong, Yang, Cai-Yun, Liu, Feng-Lin, Li, Xia, Liu, Bo, Kou, Jun-Feng, Huang, Guo-Li, Teng, Ming-Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalysis Cyclization Norbornanes - chemistry Palladium - chemistry
Online-Zugang:	Volltext
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