Enhanced apoptotic index in hepatocytes, Kupffer cells, and inflammatory infiltrate showed positive correlation with hepatic lesion intensity, parasite load, and clinical status in naturally Leishmania-infected dogs

It is unknown if Leishmania amastigote infections affect hepatocytes and Kupffer cell apoptosis, and the role played by apoptosis in liver lesions in leishmaniasis is still unclear. Clinically affected and subclinically infected dogs with leishmaniosis and uninfected controls were assessed. Parasite...

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Veröffentlicht in:	Microbial pathogenesis 2023-08, Vol.181, p.106194-106194, Article 106194
Hauptverfasser:	Verçosa, Bárbara Laurice Araujo, Muniz-Junqueira, Maria Imaculada, Mineiro, Ana Lys Bezerra Barradas, Costa, Francisco Assis Lima, Melo, Maria Norma, Vasconcelos, Anilton Cesar
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Canine leishmaniosis Dog Diseases - parasitology Dogs Hepatocytes - pathology Inflammation Kupffer Cells - pathology Leishmania infantum Leishmaniasis Leishmaniasis, Visceral - parasitology Leishmaniasis, Visceral - veterinary Liver Parasite Load - veterinary
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