Suppression of the excitability of rat nociceptive secondary sensory neurons following local administration of the Phytochemical, (-)-Epigallocatechin-3-gallate

[Display omitted] •Local EGCG injection suppressed the nociceptive TG neuronal activity.•Neuronal firing was dose-dependently inhibited by EGCG.•The inhibitory effect of EGCG lasted for 15 min and was reversible.•The potency of inhibition by EGCG almost equaled that of 1% lidocaine.•EGCG may be an e...

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Veröffentlicht in:	Brain research 2023-08, Vol.1813, p.148426-148426, Article 148426
Hauptverfasser:	Uchino, Mizuho, Sashide, Yukito, Takeda, Mamoru
Format:	Artikel
Sprache:	eng
Schlagworte:	(-)-epigallocatechin-3-gallate (EGCG) Complementary alternative medicine Extracellular unit recording Lidocaine Na+ channel Trigeminal pain
Online-Zugang:	Volltext
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