Cell surface ATP synthase-released H+ and ATP play key roles in cocoa butter intake-mediated regulation of gut immunity through releases of cytokines in rat

Proper food intake is important for maintaining good health in humans. Chocolate is known to exert anti-inflammatory effects; however, the mechanisms remain unclear. In this study, we aimed to investigate the effects of cocoa butter intake on gut immunity in rats and rabbits. Cocoa butter intake inc...

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Veröffentlicht in:	Pflügers Archiv 2023-08, Vol.475 (8), p.945-960
Hauptverfasser:	Arai, Nariaki, Kajihara, Ryo, Takasaka, Mieko, Amari, Kei, Kuneshita, Norika, Maejima, Daisuke, Watanabe-Asaka, Tomomi, Hayashi, Moyuru, Yokoyama, Yumiko, Kaidoh, Maki, Kawai, Yoshiko, Ohhashi, Toshio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals ATP synthase Biomedical and Life Sciences Biomedicine Bisphosphonates Carbon dioxide Carbon Dioxide - metabolism Cell Biology Cell density Cell surface Cells, Cultured Chocolate Clodronic Acid Cocoa Cocoa butter Cytokines Dietary Fats - administration & dosage Edible oils Food intake Gastrointestinal Tract - immunology Gastrointestinal Tract - metabolism Human Physiology Hydrogen IL-1β Immunity Inflammation Integrative Physiology Interleukin 10 Interleukin 6 Interleukin-10 - metabolism Interleukin-1beta - metabolism Interleukin-6 - metabolism Jejunum Jejunum - metabolism Lamina propria Lymph Lymph - metabolism Macrophages Male Mechanical stimuli Molecular Medicine Neurosciences Piceatannol Portal vein Proton-Translocating ATPases - antagonists & inhibitors Proton-Translocating ATPases - metabolism Rabbits Rats Rats, Sprague-Dawley Receptors Shear Strength
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