Multi-Institutional Review From the Pediatric Colorectal and Pelvic Learning Consortium of Minor Spinal Cord Dysraphism in the Setting of Anorectal Malformations: Diagnosis, Treatment, and Outcomes

Multi-Institutional Review From the Pediatric Colorectal and Pelvic Learning Consortium of Minor Spinal Cord Dysraphism in the Setting of Anorectal Malformations: Diagnosis, Treatment, and Outcomes

Anorectal malformations (ARM) are associated with congenital anomalies of the spine, but the impact of a minor spinal cord dysraphism (mSCD) on fecal continence in the setting of ARM remains unclear. A retrospective review was performed utilizing data from the Pediatric Colorectal and Pelvic Learnin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of pediatric surgery 2023-08, Vol.58 (8), p.1582-1587
Hauptverfasser: Garvey, Erin M., Fuller, Megan, Frischer, Jason, Calkins, Casey M., Rentea, Rebecca M., Ralls, Matthew, Wood, Richard, Rollins, Michael D., Avansino, Jeffrey, Reeder, Ron W., Durham, Megan M.
Format: Artikel
Sprache:eng
Schlagworte:
Anorectal malformation
Bowel management protocols
Spinal cord dysraphism
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1587
container_issue 8
container_start_page 1582
container_title Journal of pediatric surgery
container_volume 58
creator Garvey, Erin M.
Fuller, Megan
Frischer, Jason
Calkins, Casey M.
Rentea, Rebecca M.
Ralls, Matthew
Wood, Richard
Rollins, Michael D.
Avansino, Jeffrey
Reeder, Ron W.
Durham, Megan M.
description Anorectal malformations (ARM) are associated with congenital anomalies of the spine, but the impact of a minor spinal cord dysraphism (mSCD) on fecal continence in the setting of ARM remains unclear. A retrospective review was performed utilizing data from the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC) registry. The patient cohort was reviewed for ARM type, mSCD screening/incidence/neurosurgical intervention and age-based BMP utilization. 987 patients with ARM were categorized into mild (38%), moderate (32%) or complex (19%). 694 (70%) had normal spinal (NS) status. 271 (27.5%) patients had mSCD. MRI alone (49%) was the most common screening test for mSCD. US screening had a positive predictive value of 86.3% and a negative predictive value of 67.1%. Surgical intervention rates for mSCD ranged between 13% and 77% at a median age of 0.6–5.2 years. 726 (73.6%) patients were prescribed BMP (74.4% NS, 77.5% mSCD). Laxatives were most utilized BMP in all groups
doi_str_mv 10.1016/j.jpedsurg.2023.04.009
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2820971404</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0022346823002518</els_id><sourcerecordid>2820971404</sourcerecordid><originalsourceid>FETCH-LOGICAL-c315t-d46cec9c82bf4d5c544d54fd1ab776680a7598a8734a99de139fe06d2b5c4ddd3</originalsourceid><addsrcrecordid>eNqFkc1u3CAUhVHVKpkmeYWIZRexCzb-66rRpGkjzShVk6wRA9cTRgZcwInygH2v4kym225Auvfcc-B-CJ1TklNC68-7fDeCCpPf5gUpypywnJDuHVrQqqRZRcrmPVoQUhRZyer2GH0MYUdIKhN6hI7LpmAtZWSB_qynIersxoao4xS1s2LAv-BJwzO-9s7g-Aj4JygtotcSL93gPMiYRMKq1BieUnUFwlttt6ltg_NRTwa7Hq-1dR7fjXr2XDqv8NVL8GJ81MFgbV-t7yDGeTLJL-3Bei2G3nkj5ueEL_hKi611QYcLfO9BRAM2Xrzm305ROgPhFH3oxRDg7O0-QQ_X3-6XP7LV7feb5eUqkyWtYqZYLUF2si02PVOVrFg6Wa-o2DRNXbdENFXXirYpmeg6BbTseiC1KjaVZEqp8gR92vuO3v2eIERudJAwDMKCmwIv2oJ0TVosS9J6L5XeheCh56PXRvgXTgmfEfIdPyDkM0JOGE8I0-D5W8a0MaD-jR2YJcHXvQDSTxMoz4PUYGWCNO-PK6f_l_EXCme1ig</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2820971404</pqid></control><display><type>article</type><title>Multi-Institutional Review From the Pediatric Colorectal and Pelvic Learning Consortium of Minor Spinal Cord Dysraphism in the Setting of Anorectal Malformations: Diagnosis, Treatment, and Outcomes</title><source>Elsevier ScienceDirect Journals Complete</source><creator>Garvey, Erin M. ; Fuller, Megan ; Frischer, Jason ; Calkins, Casey M. ; Rentea, Rebecca M. ; Ralls, Matthew ; Wood, Richard ; Rollins, Michael D. ; Avansino, Jeffrey ; Reeder, Ron W. ; Durham, Megan M.</creator><creatorcontrib>Garvey, Erin M. ; Fuller, Megan ; Frischer, Jason ; Calkins, Casey M. ; Rentea, Rebecca M. ; Ralls, Matthew ; Wood, Richard ; Rollins, Michael D. ; Avansino, Jeffrey ; Reeder, Ron W. ; Durham, Megan M. ; For the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC) ; Pediatric Colorectal and Pelvic Learning Consortium (PCPLC)</creatorcontrib><description>Anorectal malformations (ARM) are associated with congenital anomalies of the spine, but the impact of a minor spinal cord dysraphism (mSCD) on fecal continence in the setting of ARM remains unclear. A retrospective review was performed utilizing data from the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC) registry. The patient cohort was reviewed for ARM type, mSCD screening/incidence/neurosurgical intervention and age-based BMP utilization. 987 patients with ARM were categorized into mild (38%), moderate (32%) or complex (19%). 694 (70%) had normal spinal (NS) status. 271 (27.5%) patients had mSCD. MRI alone (49%) was the most common screening test for mSCD. US screening had a positive predictive value of 86.3% and a negative predictive value of 67.1%. Surgical intervention rates for mSCD ranged between 13% and 77% at a median age of 0.6–5.2 years. 726 (73.6%) patients were prescribed BMP (74.4% NS, 77.5% mSCD). Laxatives were most utilized BMP in all groups &lt;5yo. ≥5yo, enema utilization increased with ARM complexity independent of spine status (with or without neurosurgical intervention). Neurosurgical intervention did not affect BMP utilization at any age or with any ARM when mSCD was identified. MSCD influence on bowel function in the setting ARM remains unclear. No significant impact of mSCD was noted on ARM patient bowel management program utilization. Variability exists within PCPLC site with screening and intervention for mSCD in patients with ARM. Future studies with standardized care may be needed to elucidate the true impact of mSCD on long term patient outcomes in ARM patients. Retrospective Comparative Study. III.</description><identifier>ISSN: 0022-3468</identifier><identifier>EISSN: 1531-5037</identifier><identifier>DOI: 10.1016/j.jpedsurg.2023.04.009</identifier><identifier>PMID: 37248140</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Anorectal malformation ; Bowel management protocols ; Spinal cord dysraphism</subject><ispartof>Journal of pediatric surgery, 2023-08, Vol.58 (8), p.1582-1587</ispartof><rights>2023 Elsevier Inc.</rights><rights>Copyright © 2023 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c315t-d46cec9c82bf4d5c544d54fd1ab776680a7598a8734a99de139fe06d2b5c4ddd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jpedsurg.2023.04.009$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37248140$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Garvey, Erin M.</creatorcontrib><creatorcontrib>Fuller, Megan</creatorcontrib><creatorcontrib>Frischer, Jason</creatorcontrib><creatorcontrib>Calkins, Casey M.</creatorcontrib><creatorcontrib>Rentea, Rebecca M.</creatorcontrib><creatorcontrib>Ralls, Matthew</creatorcontrib><creatorcontrib>Wood, Richard</creatorcontrib><creatorcontrib>Rollins, Michael D.</creatorcontrib><creatorcontrib>Avansino, Jeffrey</creatorcontrib><creatorcontrib>Reeder, Ron W.</creatorcontrib><creatorcontrib>Durham, Megan M.</creatorcontrib><creatorcontrib>For the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC)</creatorcontrib><creatorcontrib>Pediatric Colorectal and Pelvic Learning Consortium (PCPLC)</creatorcontrib><title>Multi-Institutional Review From the Pediatric Colorectal and Pelvic Learning Consortium of Minor Spinal Cord Dysraphism in the Setting of Anorectal Malformations: Diagnosis, Treatment, and Outcomes</title><title>Journal of pediatric surgery</title><addtitle>J Pediatr Surg</addtitle><description>Anorectal malformations (ARM) are associated with congenital anomalies of the spine, but the impact of a minor spinal cord dysraphism (mSCD) on fecal continence in the setting of ARM remains unclear. A retrospective review was performed utilizing data from the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC) registry. The patient cohort was reviewed for ARM type, mSCD screening/incidence/neurosurgical intervention and age-based BMP utilization. 987 patients with ARM were categorized into mild (38%), moderate (32%) or complex (19%). 694 (70%) had normal spinal (NS) status. 271 (27.5%) patients had mSCD. MRI alone (49%) was the most common screening test for mSCD. US screening had a positive predictive value of 86.3% and a negative predictive value of 67.1%. Surgical intervention rates for mSCD ranged between 13% and 77% at a median age of 0.6–5.2 years. 726 (73.6%) patients were prescribed BMP (74.4% NS, 77.5% mSCD). Laxatives were most utilized BMP in all groups &lt;5yo. ≥5yo, enema utilization increased with ARM complexity independent of spine status (with or without neurosurgical intervention). Neurosurgical intervention did not affect BMP utilization at any age or with any ARM when mSCD was identified. MSCD influence on bowel function in the setting ARM remains unclear. No significant impact of mSCD was noted on ARM patient bowel management program utilization. Variability exists within PCPLC site with screening and intervention for mSCD in patients with ARM. Future studies with standardized care may be needed to elucidate the true impact of mSCD on long term patient outcomes in ARM patients. Retrospective Comparative Study. III.</description><subject>Anorectal malformation</subject><subject>Bowel management protocols</subject><subject>Spinal cord dysraphism</subject><issn>0022-3468</issn><issn>1531-5037</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNqFkc1u3CAUhVHVKpkmeYWIZRexCzb-66rRpGkjzShVk6wRA9cTRgZcwInygH2v4kym225Auvfcc-B-CJ1TklNC68-7fDeCCpPf5gUpypywnJDuHVrQqqRZRcrmPVoQUhRZyer2GH0MYUdIKhN6hI7LpmAtZWSB_qynIersxoao4xS1s2LAv-BJwzO-9s7g-Aj4JygtotcSL93gPMiYRMKq1BieUnUFwlttt6ltg_NRTwa7Hq-1dR7fjXr2XDqv8NVL8GJ81MFgbV-t7yDGeTLJL-3Bei2G3nkj5ueEL_hKi611QYcLfO9BRAM2Xrzm305ROgPhFH3oxRDg7O0-QQ_X3-6XP7LV7feb5eUqkyWtYqZYLUF2si02PVOVrFg6Wa-o2DRNXbdENFXXirYpmeg6BbTseiC1KjaVZEqp8gR92vuO3v2eIERudJAwDMKCmwIv2oJ0TVosS9J6L5XeheCh56PXRvgXTgmfEfIdPyDkM0JOGE8I0-D5W8a0MaD-jR2YJcHXvQDSTxMoz4PUYGWCNO-PK6f_l_EXCme1ig</recordid><startdate>202308</startdate><enddate>202308</enddate><creator>Garvey, Erin M.</creator><creator>Fuller, Megan</creator><creator>Frischer, Jason</creator><creator>Calkins, Casey M.</creator><creator>Rentea, Rebecca M.</creator><creator>Ralls, Matthew</creator><creator>Wood, Richard</creator><creator>Rollins, Michael D.</creator><creator>Avansino, Jeffrey</creator><creator>Reeder, Ron W.</creator><creator>Durham, Megan M.</creator><general>Elsevier Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202308</creationdate><title>Multi-Institutional Review From the Pediatric Colorectal and Pelvic Learning Consortium of Minor Spinal Cord Dysraphism in the Setting of Anorectal Malformations: Diagnosis, Treatment, and Outcomes</title><author>Garvey, Erin M. ; Fuller, Megan ; Frischer, Jason ; Calkins, Casey M. ; Rentea, Rebecca M. ; Ralls, Matthew ; Wood, Richard ; Rollins, Michael D. ; Avansino, Jeffrey ; Reeder, Ron W. ; Durham, Megan M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c315t-d46cec9c82bf4d5c544d54fd1ab776680a7598a8734a99de139fe06d2b5c4ddd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Anorectal malformation</topic><topic>Bowel management protocols</topic><topic>Spinal cord dysraphism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Garvey, Erin M.</creatorcontrib><creatorcontrib>Fuller, Megan</creatorcontrib><creatorcontrib>Frischer, Jason</creatorcontrib><creatorcontrib>Calkins, Casey M.</creatorcontrib><creatorcontrib>Rentea, Rebecca M.</creatorcontrib><creatorcontrib>Ralls, Matthew</creatorcontrib><creatorcontrib>Wood, Richard</creatorcontrib><creatorcontrib>Rollins, Michael D.</creatorcontrib><creatorcontrib>Avansino, Jeffrey</creatorcontrib><creatorcontrib>Reeder, Ron W.</creatorcontrib><creatorcontrib>Durham, Megan M.</creatorcontrib><creatorcontrib>For the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC)</creatorcontrib><creatorcontrib>Pediatric Colorectal and Pelvic Learning Consortium (PCPLC)</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pediatric surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Garvey, Erin M.</au><au>Fuller, Megan</au><au>Frischer, Jason</au><au>Calkins, Casey M.</au><au>Rentea, Rebecca M.</au><au>Ralls, Matthew</au><au>Wood, Richard</au><au>Rollins, Michael D.</au><au>Avansino, Jeffrey</au><au>Reeder, Ron W.</au><au>Durham, Megan M.</au><aucorp>For the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC)</aucorp><aucorp>Pediatric Colorectal and Pelvic Learning Consortium (PCPLC)</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multi-Institutional Review From the Pediatric Colorectal and Pelvic Learning Consortium of Minor Spinal Cord Dysraphism in the Setting of Anorectal Malformations: Diagnosis, Treatment, and Outcomes</atitle><jtitle>Journal of pediatric surgery</jtitle><addtitle>J Pediatr Surg</addtitle><date>2023-08</date><risdate>2023</risdate><volume>58</volume><issue>8</issue><spage>1582</spage><epage>1587</epage><pages>1582-1587</pages><issn>0022-3468</issn><eissn>1531-5037</eissn><abstract>Anorectal malformations (ARM) are associated with congenital anomalies of the spine, but the impact of a minor spinal cord dysraphism (mSCD) on fecal continence in the setting of ARM remains unclear. A retrospective review was performed utilizing data from the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC) registry. The patient cohort was reviewed for ARM type, mSCD screening/incidence/neurosurgical intervention and age-based BMP utilization. 987 patients with ARM were categorized into mild (38%), moderate (32%) or complex (19%). 694 (70%) had normal spinal (NS) status. 271 (27.5%) patients had mSCD. MRI alone (49%) was the most common screening test for mSCD. US screening had a positive predictive value of 86.3% and a negative predictive value of 67.1%. Surgical intervention rates for mSCD ranged between 13% and 77% at a median age of 0.6–5.2 years. 726 (73.6%) patients were prescribed BMP (74.4% NS, 77.5% mSCD). Laxatives were most utilized BMP in all groups &lt;5yo. ≥5yo, enema utilization increased with ARM complexity independent of spine status (with or without neurosurgical intervention). Neurosurgical intervention did not affect BMP utilization at any age or with any ARM when mSCD was identified. MSCD influence on bowel function in the setting ARM remains unclear. No significant impact of mSCD was noted on ARM patient bowel management program utilization. Variability exists within PCPLC site with screening and intervention for mSCD in patients with ARM. Future studies with standardized care may be needed to elucidate the true impact of mSCD on long term patient outcomes in ARM patients. Retrospective Comparative Study. III.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>37248140</pmid><doi>10.1016/j.jpedsurg.2023.04.009</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0022-3468
ispartof Journal of pediatric surgery, 2023-08, Vol.58 (8), p.1582-1587
issn 0022-3468
1531-5037
language eng
recordid cdi_proquest_miscellaneous_2820971404
source Elsevier ScienceDirect Journals Complete
subjects Anorectal malformation
Bowel management protocols
Spinal cord dysraphism
title Multi-Institutional Review From the Pediatric Colorectal and Pelvic Learning Consortium of Minor Spinal Cord Dysraphism in the Setting of Anorectal Malformations: Diagnosis, Treatment, and Outcomes
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T19%3A11%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Multi-Institutional%20Review%20From%20the%20Pediatric%20Colorectal%20and%20Pelvic%20Learning%20Consortium%20of%20Minor%20Spinal%20Cord%20Dysraphism%20in%20the%20Setting%20of%20Anorectal%20Malformations:%20Diagnosis,%20Treatment,%20and%20Outcomes&rft.jtitle=Journal%20of%20pediatric%20surgery&rft.au=Garvey,%20Erin%20M.&rft.aucorp=For%20the%20Pediatric%20Colorectal%20and%20Pelvic%20Learning%20Consortium%20(PCPLC)&rft.date=2023-08&rft.volume=58&rft.issue=8&rft.spage=1582&rft.epage=1587&rft.pages=1582-1587&rft.issn=0022-3468&rft.eissn=1531-5037&rft_id=info:doi/10.1016/j.jpedsurg.2023.04.009&rft_dat=%3Cproquest_cross%3E2820971404%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2820971404&rft_id=info:pmid/37248140&rft_els_id=S0022346823002518&rfr_iscdi=true