Excitatory GluN1/GluN3A glycine receptors (eGlyRs) in brain signaling

Association of the NMDA receptor (NMDAR) subunit GluN3A with GluN1 leads to the formation of GluN1/GluN3A excitatory glycine receptors (eGlyRs), the properties of which differ strikingly from those of ‘conventional’ GluN1/GluN2 NMDARs.eGlyRs are bona fide brain receptors that are functionally expres...

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Veröffentlicht in:	Trends in neurosciences (Regular ed.) 2023-08, Vol.46 (8), p.667-681
Hauptverfasser:	Bossi, Simon, Pizzamiglio, Lara, Paoletti, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain - metabolism extrasynaptic receptors GluN3A glycine Glycine - metabolism Glycine - pharmacology Humans neuronal excitability Neurons - metabolism neurotransmission NMDA receptors Receptors, Glycine - metabolism Receptors, N-Methyl-D-Aspartate
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