Comparison of a modified pediatric protocol versus a hyper-CVAD protocol in adolescents and young adults with Philadelphia-negative acute lymphoblastic leukemia: A multicenter retrospective analysis

The outcomes of Pediatric acute lymphoblastic leukemia (ALL) have improved dramatically whereas outcomes for ALL amongst adolescents and young adults (AYA) have lagged behind. The introduction of pediatric-like regimens to manage adult ALL has shown promising outcomes across several analyses. In thi...

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Veröffentlicht in:	Leukemia research 2023-07, Vol.130, p.107316-107316, Article 107316
Hauptverfasser:	Salama, Hind, Eldadah, Saleem, Omer, Mohamed H., Alhejazi, Ayman, Bin Dayil, Luluh, Almozaini, Ayman, Khalil, Roaa Reda, Mugairi, Areej Al, Snnallah, Mohammed, Damlaj, Moussab, Alaskar, Ahmed, Alsaeed, Ahmad, Bakkar, Mohammed Mosa, Alahmari, Bader, Alzahrani, Mohsen, Elhemaidi, Ihab, Alahmadi, Majed, Alamoudi, Sameer, Rajkhan, Walaa, Khalil, Manar, Kanfar, Solaf Sami, Saleh, Abdullah S. Al, Raizah, Abdulrahman Al, Ibrahim, Ayman, Absi, Ahmed
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute lymphoblastic leukemia Adolescent Adolescents and young adults Antineoplastic Combined Chemotherapy Protocols - adverse effects BFM Child Cyclophosphamide - therapeutic use Dexamethasone - adverse effects Doxorubicin - therapeutic use Humans HyperCVAD Multicenter Studies as Topic Pediatric protocols Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Retrospective Studies Vincristine - therapeutic use Young Adult
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