Sustained inhibition of complement C1s with sutimlimab over 2 years in patients with cold agglutinin disease

Cold agglutinin disease (CAD) is a rare, autoimmune, classical complement pathway (CP)-mediated hemolytic anemia. Sutimlimab selectively inhibits C1s of the C1 complex, preventing CP activation while leaving the alternative and lectin pathways intact. In Part A (26 weeks) of the open-label, single-a...

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Veröffentlicht in:	American journal of hematology 2023-08, Vol.98 (8), p.1246-1253
Hauptverfasser:	Röth, Alexander, Barcellini, Wilma, D'Sa, Shirley, Miyakawa, Yoshitaka, Broome, Catherine M, Michel, Marc, Kuter, David J, Jilma, Bernd, Tvedt, Tor Henrik Anderson, Weitz, Ilene C, Yoo, Ronnie, Jayawardene, Deepthi, Vagge, Deepthi S, Kralova, Katarina, Shafer, Frank, Wardȩcki, Marek, Lee, Michelle, Berentsen, Sigbjørn
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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