Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development

Abstract Reticulon (RTN) proteins are a family of proteins biochemically identified for shaping tubular endoplasmic reticulum, a subcellular structure important for vesicular transport and cell-to-cell communication. In our recent study of mice with knockout of both reticulon 1 (Rtn1) and Rtn3, we d...

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Veröffentlicht in:	Human molecular genetics 2023-08, Vol.32 (16), p.2587-2599
Hauptverfasser:	Zhou, John, Shi, Qi, Ge, Ying Y, He, Wanxia, Hu, Xiangyou, Xia, Weiming, Yan, Riqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - metabolism Axons - pathology Cytoskeleton - metabolism Cytoskeleton - pathology Endoplasmic Reticulum - metabolism Genes, Lethal Hippocampus - metabolism Hippocampus - pathology Mice Mice, Knockout Nerve Tissue Proteins - metabolism Synapses
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